Prof. Staibano Stefania

Prof. Staibano Stefania

Associate Professor of Pathology

University Federico II Department of Biomorpgological and Functional Sciences Pathology Section
Via Pansini 5, 0, Italy, 8031

plus Speciality

PATHOLOGY

Biography:

Stefania Staibano, MD, PHD

Medical Doctor (1982), Post-Graduate in Pathology, Post-Graduate in Surgical Pathology, PhD in Pathological Sciences; Associate Professor of Pathology at the University of Naples “Federico II”, Naples, Italy; Chief of the Head and Neck Pathology Section at the Department of Surgical Pathology of the Federico II University of Naples, Italy. Member of the Austrian-Italian web-consensus panel of pathologists for the dermoscopic and histologic correlations of pigmented skin tumors,.coordinated by Prof. H. Peter Soyer, University of Queensland South Brisbane Area, Australia. STUDY GROUP MEMBERSHIPS: Study Group on morphological features and the expression of new molecular prognostic biomarkers in oral cancers and related preneoplastic lesions (collaboration with: Umea University, Sweden, and Hiroshima University, Japan); Study group (coordinated by Prof. Dario C. Altieri, MD, Department of Cancer Biology and the Cancer Center, University of Massachusetts Medical School), on the cellular and molecular mechanisms of inhibition of apoptosis in squamous cell carcinoma; collaboration with Prof. Crispian Scully, Eastman Dental Institute for Oral Health Care Science, London; Cooperative Study Group on Cutaneous Melanoma of the Federico II University, Naples, Italy. Editor and/or peer reviewer for international scientific journals indexed in MEDLINE, with IF (Clin Cancer Res, Human Pathol, Histopathology, Oral Pathology, et al.). Author of >130 articles published on peer-reviewed international scientific journals indexed in MEDLINE with IF. Co-author of scientific books and monographies. Main research field: neoplastic progression of solid tumors, new prognostic biomarkers for cancer, immunohistochemistry. Peer-referee for national and international scientific projects. Principal investigator or member of local units in research projects funded by Italian ministry of University and Research (MIUR) and Regione Campania. Member of the European Society of Pathology (ESP), and of the Italian Society of Pathological Anatomy and Cytology (IAP/SIAPEC).

Academic positions:

Associate Professor of Pathology

Chief of the Head and Neck Pathology Section

University Federico II of Naples - School of Medicine

Italy

Research interests:

Pathology

Tumor progression

Immunohistochemistry

Molecular biology

Prognostic biomarkers

Melanoma

HPV

Head and Neck cancer

Any other information:

Publications

1. Ilardi G, Zambrano N, Merolla F, Siano M, Varricchio S, Vecchione M, De Rosa G, Mascolo M, Staibano S. Histopathological Determinants of Tumor Resistance: a Special Look to The Immunohistochemical Expression of Carbonic Anhydrase IX in Human Cancers. Curr Med Chem. 2013 Aug 23. [Epub ahead of print] PubMed PMID: 23992304.
2. Andria B, Bracco A, Attanasio C, Castaldo S, Cerrito MG, Cozzolino S, Di Napoli D, Giovannoni R, Mancini A, Musumeci A, Mezza E, Nasti M, Scuderi V, Staibano S, Lavitrano M, Otterbein LE, Calise F. Biliverdin Protects against Liver Ischemia Reperfusion Injury in Swine. PLoS One. 2013 Jul 29;8(7):e69972. doi: 10.1371/journal.pone.0069972. Print 2013. PubMed PMID: 23922878; PubMed Central PMCID: PMC3726748.
3. Romano S, Nappo G, Calì G, Wang SY, Staibano S, D'Angelillo A, Ilardi G, Sorrentino A, Di Pace AL, Siano M, Bisogni R, Romano MF. Synergy between enzastaurin doxorubicin in inducing melanoma apoptosis. Pigment Cell Melanoma Res. 2013 Jul 19. doi: 10.1111/pcmr.12144. [Epub ahead of print] PubMed PMID: 23866034.
4. Cerrone M, Collina F, De Chiara A, Corazzelli G, Curcio MP, De Renzo A, Russo  F, Cantile M, Staibano S, Strianese D, Tranfa F, Botti G, De Rosa G, Franco R. BCL10 expression and localization in Ocular Adnexa MALT lymphomas: a comparative  cytogenetic and immunohistochemical study. Histol Histopathol. 2013 Jul 12. [Epub ahead of print] PubMed PMID: 23846624.
5. Romano S, Staibano S, Greco A, Brunetti A, Nappo G, Ilardi G, Martinelli R, Sorrentino A, Di Pace A, Mascolo M, Bisogni R, Scalvenzi M, Alfano B, Romano MF. FK506 binding protein 51 positively regulates melanoma stemness and metastatic potential. Cell Death Dis. 2013 Apr 4;4:e578. doi: 10.1038/cddis.2013.109. PubMed PMID: 23559012; PubMed Central PMCID: PMC3641332.
6. Scalvenzi M, Palmisano F, Cacciapuoti S, Migliaro F, Siano M, Staibano S, Tornillo L, Costa C. Giant congenital melanocytic naevus with proliferative nodules mimicking congenital malignant melanoma: a case report and review of the  literature of congenital melanoma. Case Rep Dermatol Med. 2013;2013:473635. doi: 10.1155/2013/473635. Epub 2013 Jan 16. PubMed PMID: 23401804; PubMed Central PMCID: PMC3562615.
7. Simonetti O, Lucarini G, Rubini C, Goteri G, Zizzi A, Staibano S, Campanati A, Ganzetti G, Di Primio R, Offidani A. Microvessel density and VEGF, HIF-1α expression in primary oral melanoma: correlation with prognosis. Oral Dis. 2013 Sep;19(6):620-7. doi: 10.1111/odi.12048. Epub 2012 Dec 27. PubMed PMID: 23279259.
8. Gunia S, Erbersdobler A, Koch S, Otto W, Staibano S, D'Alterio C, Brookman-May S. Protein gene product 9.5 is diagnostically helpful in delineating high-grade renal cell cancer involving the renal medullary/sinus region from invasive urothelial cell carcinoma of the renal pelvis. Hum Pathol. 2013 May;44(5):712-7. doi: 10.1016/j.humpath.2012.07.024. Epub 2012 Nov 14. PubMed PMID: 23158209.
9. Rispo A, Castiglione F, Staibano S, Esposito D, Maione F, Siano M, Salvatori F, Masone S, Persico M, De Palma GD. Diagnostic accuracy of confocal laser endomicroscopy in diagnosing dysplasia in patients affected by long-standing ulcerative colitis. World J Gastrointest Endosc. 2012 Sep 16;4(9):414-20. doi: 10.4253/wjge.v4.i9.414. PubMed PMID: 23125900; PubMed Central PMCID: PMC3487190.
10. Mascolo M, Ilardi G, Merolla F, Russo D, Vecchione ML, de Rosa G, Staibano S. Tissue Microarray-Based Evaluation of Chromatin Assembly Factor-1 (CAF-1)/p60 as Tumour Prognostic Marker. Int J Mol Sci. 2012;13(9):11044-62. doi: 10.3390/ijms130911044. Epub 2012 Sep 5. PubMed PMID: 23109837; PubMed Central PMCID: PMC3472729.
11. Mascolo M, Ilardi G, Romano MF, Celetti A, Siano M, Romano S, Luise C, Merolla F, Rocco A, Vecchione ML, De Rosa G, Staibano S. Overexpression of chromatin assembly factor-1 p60, poly(ADP-ribose) polymerase 1 and nestin predicts metastasizing behaviour of oral cancer. Histopathology. 2012 Dec;61(6):1089-105. doi: 10.1111/j.1365-2559.2012.04313.x. Epub 2012 Aug 8. PubMed PMID: 22882088; PubMed Central PMCID: PMC3546388.
12. Aquino G, Pannone G, Santoro A, Liguori G, Franco R, Serpico R, Florio G, De  Rosa A, Mattoni M, Cozza V, Botti G, Losito S, Longo F, Staibano S, Cuda G, Lo Muzio L, Sbordone C, Bufo P, Grimaldi A, Caraglia M, Di Domenico M. pEGFR-Tyr 845 expression as prognostic factors in oral squamous cell carcinoma: a tissue-microarray study with clinic-pathological correlations. Cancer Biol Ther. 2012 Sep;13(11):967-77. doi: 10.4161/cbt.20991. Epub 2012 Jul 24. PubMed PMID: 22825335; PubMed Central PMCID: PMC3461819.
13. Rocco A, Compare D, Liguori E, Cianflone A, Pirozzi G, Tirino V, Bertoni A, Santoriello M, Garbi C, D'Armiento M, Staibano S, Nardone G. MDR1-P-glycoprotein behaves as an oncofetal protein that promotes cell survival in gastric cancer cells. Lab Invest. 2012 Oct;92(10):1407-18. doi: 10.1038/labinvest.2012.100. Epub 2012 Jul 2. PubMed PMID: 22751348.
14. Caracò C, Mozzillo N, Di Monta G, Botti G, Anniciello AM, Marone U, Di Cecilia ML, Staibano S, De Rosa G. Sentinel lymph node biopsy in atypical Spitz nevi: is it useful? Eur J Surg Oncol. 2012 Oct;38(10):932-5. doi: 10.1016/j.ejso.2012.05.010. Epub 2012 Jun 14. PubMed PMID: 22704051.
15. Colombino M, Capone M, Lissia A, Cossu A, Rubino C, De Giorgi V, Massi D, Fonsatti E, Staibano S, Nappi O, Pagani E, Casula M, Manca A, Sini M, Franco R, Botti G, Caracò C, Mozzillo N, Ascierto PA, Palmieri G. BRAF/NRAS mutation frequencies among primary tumors and metastases in patients with melanoma. J Clin Oncol. 2012 Jul 10;30(20):2522-9. doi: 10.1200/JCO.2011.41.2452. Epub 2012 May 21. PubMed PMID: 22614978.
16. Simeone E, De Maio E, Sandomenico F, Fulciniti F, Lastoria S, Aprea P, Staibano S, Montesarchio V, Palmieri G, Mozzillo N, Ascierto PA. Neoplastic leptomeningitis presenting in a melanoma patient treated with dabrafenib (aV600EBRAF inhibitor): a case report. J Med Case Rep. 2012 May 17;6(1):131. doi: 10.1186/1752-1947-6-131. PubMed PMID: 22594466; PubMed Central PMCID: PMC3423050.
17. Mascolo M, Staibano S, Ilardi G, Siano M, Vecchione ML, Esposito D, De Rosa G, De Palma GD. Probe-based confocal laser endomicroscopy evaluation of colon preneoplastic lesions, with particular attention to the aberrant crypt foci, and comparative assessment with histological features obtained by conventional endoscopy. Gastroenterol Res Pract. 2012;2012:645173. doi: 10.1155/2012/645173. Epub 2012 Apr 8. PubMed PMID: 22566999; PubMed Central PMCID: PMC3328946.
18. Mascolo M, Siano M, Ilardi G, Russo D, Merolla F, De Rosa G, Staibano S. Epigenetic disregulation in oral cancer. Int J Mol Sci. 2012;13(2):2331-53. doi: 10.3390/ijms13022331. Epub 2012 Feb 21. PubMed PMID: 22408457; PubMed Central PMCID: PMC3292026.
19. Pannone G, Rodolico V, Santoro A, Lo Muzio L, Franco R, Botti G, Aquino G, Pedicillo MC, Cagiano S, Campisi G, Rubini C, Papagerakis S, De Rosa G, Tornesello ML, Buonaguro FM, Staibano S, Bufo P. Evaluation of a combined triple method to detect causative HPV in oral and oropharyngeal squamous cell carcinomas: p16 Immunohistochemistry, Consensus PCR HPV-DNA, and In Situ Hybridization. Infect Agent Cancer. 2012 Feb 29;7:4. doi: 10.1186/1750-9378-7-4.
PubMed PMID: 22376902; PubMed Central PMCID: PMC3313884.
20. Argenziano G, Cerroni L, Zalaudek I, Staibano S, Hofmann-Wellenhof R, Arpaia  N, Bakos RM, Balme B, Bandic J, Bandelloni R, Brunasso AM, Cabo H, Calcara DA, Carlos-Ortega B, Carvalho AC, Casas G, Dong H, Ferrara G, Filotico R, Gómez G, Halpern A, Ilardi G, Ishiko A, Kandiloglu G, Kawasaki H, Kobayashi K, Koga H, Kovalyshyn I, Langford D, Liu X, Marghoob AA, Mascolo M, Massone C, Mazzoni L, Menzies S, Minagawa A, Nugnes L, Ozdemir F, Pellacani G, Seidenari S, Siamas K, Stanganelli I, Stoecker WV, Tanaka M, Thomas L, Tschandl P, Kittler H. Accuracy
in melanoma detection: a 10-year multicenter survey. J Am Acad Dermatol. 2012 Jul;67(1):54-9. doi: 10.1016/j.jaad.2011.07.019. Epub 2011 Oct 6. PubMed PMID: 21982636.
21. Baroni A, Staibano S, Russo T, Piccolo V, Satriano RA, Vozza A, Vozza G. Verrucous epidermal naevus and naevus spilus associated with lower limb asymmetry and right bundle-branch block: a case of phacomatosis pigmentokeratotica? Clin Exp Dermatol. 2012 Jan;37(1):74-5. doi: 10.1111/j.1365-2230.2011.04134.x. Epub 2011 Jul 25. PubMed PMID: 21790731.
22. Insabato L, Masone S, Campione S, Vigliar E, Staibano S, Tornillo L. Coexistence of primary gastric giant cell-rich leiomyosarcoma and gastrointestinal stromal tumor: report of a very rare combination and review of the literature. Int J Surg Pathol. 2012 Feb;20(1):74-8. doi: 10.1177/1066896911414018. Epub 2011 Jul 7. Review. PubMed PMID: 21742646.
23. Andolfo I, De Martino D, Liguori L, Petrosino G, Troncone G, Tata N, Galasso  A, Roma C, Chiancone F, Zarrilli S, Arrigoni G, Staibano S, Imbimbo C, Zollo M. Correlation of NM23-H1 cytoplasmic expression with metastatic stage in human prostate cancer tissue. Naunyn Schmiedebergs Arch Pharmacol. 2011 Oct;384(4-5):489-98. doi: 10.1007/s00210-011-0645-7. Epub 2011 May 7. PubMed PMID: 21553004.
24. Staibano S, Mascolo M, Ilardi G, Siano M, De Rosa G. Immunohistochemical analysis of FKBP51 in human cancers. Curr Opin Pharmacol. 2011 Aug;11(4):338-47. doi: 10.1016/j.coph.2011.04.001. Epub 2011 Apr 27. Review. PubMed PMID: 21530399.
25: Romano S, D'Angelillo A, Staibano S, Ilardi G, Romano MF. FK506-binding protein 51 is a possible novel tumoral marker. Cell Death Dis. 2010 Jul 15;1:e55. doi: 10.1038/cddis.2010.32. PubMed PMID: 21364660; PubMed Central PMCID: PMC3032557.

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