Dr. Bhambhani Akhilesh

Dr. Bhambhani Akhilesh

Seniro Research Chemist

770 Sumneytown Pike, WP78A-31, West Point, United States of America, 19486

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Akhilesh Bhambhani, PhD is a Senior Research Chemist at the Merck & Co., Inc., (West Point,PA). He earned his B.S. in Chemical Engineering in 2001 fromUjjain Engineering College,Indiaand his PhD in Biological Chemistry in 2006 fromUniversityofConnecticut(Storrs,CT).  Prior to joining Merck in 2009, Akhilesh worked as a postdoctoral researcher at The University of Kansas (Lawrence, KS) and later as a Development Scientist I at Amylin Pharmaceuticals (San Diego, CA) developing various liquid and lyophilized products for biologics including high concentration antibody formulation and formulations of peptides, proteins, bacteria and vaccines. In his current role, he is primarily focused on New Drying Technology development and the development of a platform lyophilized formulation for therapeutic drug candidates at high concentration, lyophilization cycle and process development. His expertise in this area was recently recognized by Merck with an "award of excellence".

Academic positions:

Academic History:

Post-Doctoral Researcher, Macromolecule and Vaccine Stabilization laboratory, Dr. Middaughs’ Lab, Pharmaceutical Chemistry, KU, KS-66047. Jan 2007 - April 2008

Doctorate of Philosophy, Biological Chemistry, December 2006

University ofConnecticut,Storrs,CT,USA; GPA: 3.84/ 4.0

Dissertation: “Novel bioactive enzyme/DNA/inorganic nano-biocomposite materials”

Bachelor of Engineering, Chemical Engineering June 2001       

UjjainEngineeringCollege, Ujjain, (M.P.), India; with Distinction

Dissertation: “Manufacture of High Fructose Corn Syrup”

Research interests:

Nano-biocomposite Materials, Enzymology, Immunoassay, Monoclonal antibody development, Process optimization, Deviation management, Combo formulation, Device development, Biophysical characterization, Preformulation /Formulation, New technology selection, Lyophilization cycle development, High throughput screening         

Any other information:

Current Role: Senior Research Chemist, Merck and Company, West Point, PA

Senior Research Chemist with expertise in Product Development and manufacturing support of vaccine and therapeutic proteins including novels and biosimilars

Expertise in liquid and lyophilized formulation development of macromolecules

Published > 20 research articles, reviews and book chapters, filed 2 patent application and 2 CMIs pending

Top Reviewer for Journal of Pharmaceutical Science, 2009

What I think of the idea behind WebmedCentral and WebmedCentral plus:

I support the ideas behind plus to, "build a community of scientists, who believe in its publishing model, to support and facilitate a vibrant culture of post publication peer review".