Dr. Jena N.R.

Dr. Jena N.R.

Assistant Professor

PDPM-IIITDMJ
Dumna Airport Road, Khameria, Jabalpur, jabalpur, India, 482005

plus Speciality

BIOPHYSICS

Biography:

Dr Jena has completed his PhD degree in Physics from Banaras Hindu University, India in 2006. Soon after finishing his PhD, he has worked as a postdoctoral fellow in several reputed institutes abroad and is a recipient of many national and international scientific awards. The current research interest of Dr Jena is to understand DNA damage and repair as well as protein-inhibitor binding at the molecular level by applying various computational tools.

Academic positions:

Education:

1. BSc, Utkal University (1999).
2. MSc, Utkal University (2001).
3. PhD, Banaras Hindu University (2006).

Professional Experience:

1. Assistant Professor: IIITDM Jabalpur, India (since Sept 2011).
2. Lecturer, Ravenshaw University, Cuttack, India (May, 2011-Sept, 2011).
3. Research Scientist, Indian Institute of Science, Bangalore, India (Oct, 2009-April, 2011).
4. Postdoc, National Taiwan Normal University, Taipei, Taiwan (Sept, 2008-Sept, 2009).
5. Guest Scientist, German Cancer Research Center, Heidelberg, Germany (June, 2008-Sept, 2008).
6. Postdoc, Hebrew University of Jerusalem, Jerusalem, Israel (May, 2007-June, 2008).

Honours, Fellowships:

1. Indo-Australia Early Career Visiting Fellowship, from INSA, India (2012-2013).
2. International Travel Award to Visit Beijing, China, from DST, India (2011).
3. 2000 Outstanding Intellectuals of the Twenty First Century by International Biography Center, London (2011).
4. Biography published in International Biography Center, London (2011).
5. Biography published in Marquis Who’s Who in the World (2010).
6. Young Scientist Award by Indian Science Congress (2007).
7. Late Shri Harbansh Singh Memorial Best Young Scientist Award by Laser & Spectroscopy Society of India (2007).
8. CSIR SRF Award (2007).
9. Best Poster Award (2005)
10. Qualified in Graduate Aptitude Test in Engineering (GATE-2003).

Research interests:

DNA damage and repair, Protein-inhibitor binding, Computational Biophysics

Any other information:

Publications:

In Peer Reviewed Journals

5. N.R. Jena, P.C. Mishra (2012) Formation of Ring-opened and Rearranged Products of Guanine: Mechanisms and Biological Significance. Free Radic. Biol. Med. 53, 81-94.
6. N.R. Jena (2012) DNA Damage by Reactive Species: Mechanisms, Mutation and Repair. J. Biosci. 37, 1-15.
7. N.R. Jena (2012) Binding of Bis Like and Other Ligands with the GSK-3β Kinase: A Combined Docking and Molecular Dynamics Study. J. Mol. Model. 18, 631-644.
8. N.R. Jena, Manju Bansal (2011) Mutagenicity Associated with O6-Methylguanine DNA Damage and Mechanism of Nucleotide Flipping by AGT During Repair. Phys. Biol. 8, 046007.
9. P.K. Shukla, N.R. Jena, P.C. Mishra (2011) Quantum Theoretical Study of Molecular Mechanisms of Mutation and Cancer: A review. Proc. Natl. Acad. Sc. A (India), 81A, 79-98.
10. N.R. Jena, P.S. Shukla, H.S. Jena, P.C. Mishra, S. Suhai (2009) O6-Methylguanine Repair by O6-Alkylguanine Alkyl Transferase. J. Phys. Chem. B 113, 16285-16290.
11. W.-H. Wang, N.R. Jena, Y.-C. Wang, Y.-C. Sun (2009) A 3D-QSAR study of Celebrex-based PDK1 Inhibitors Using CoMFA Method. J. Chin. Chem. Soc. 56, 59-64.
12. N.R. Jena, P.C. Mishra, S. Suhai (2009) Protection against Radiation-Induced DNA Damage by Amino Acids: A DFT Study. J. Phys. Chem. B 113, 5633-5644.
13. N.R. Jena, P.C. Mishra (2009) Interactions of Guanine, Its Anions and Radicals with Lysine in Different Charge States. J. Phys. Chem. B 2009, 11, 5418-5424.
14. N.R. Jena, P.C. Mishra (2008) Reaction of Hypochlorous Acid with Imidazole: Formation of 2-Chloro and 2-Oxoimidazoles. J. Comput. Chem. 29, 98-107.
15. N.R. Jena, P.C. Mishra (2007) Formation of 8-Nitroguanine and 8-Oxoguanine Due to Reactions of Peroxynitrite with Guanine. J. Comput. Chem. 28, 1321-1335.
16. N.R. Jena, P.C. Mishra (2007) A Theoretical Study of Some New Analogues of the Anti-Cancer Drug Camptothecine. J. Mol. Model. 13, 267-274.
17. N.R. Jena, P.C. Mishra (2006) Addition and Hydrogen Abstraction reactions of an OH Radical with 8-oxoguanine. Chem. Phys. Letts. 422, 417-423.
18. N.R. Jena, P.C. Mishra (2005) Mechanisms of Formation of 8-oxoguanine Due to Reactions of One and Two OH Radicals and the H2O2 Molecule with Guanine: A Quantum Computational Study. J. Phys. Chem. B 109, 14205-14218.
19. N.R. Jena, P.C. Mishra (2005) An ab-initio and Density Functional Study of Microsolvation of Carbon Dioxide in Water Clusters and Formation of Carbonic Acid. Theor. Chem. Accts. 114, 189-199.
20. N.R. Jena, P.C. Mishra (2005) Study of Relationship of Atomic Orbital Hybridization with Bonding Using Hybridization Displacement Charge: Optimal Hybridization Principle. J. Mol. Struct. (Theochem) 719, 75-84.

In Conference Abstracts or Proceedings:

21. N.R. Jena (2012) Mechanisms of Lesion Recognition and Repair by AGT, National Symposium on “Advances in Laser and Spectroscopy”, ISM Dhanbad, India.
22. N.R. Jena (2011) DNA Damage by Reactive Species: Mechanisms, Mutation and Repair, International Conference on “Disorders in Nucleic Acids and Disease”, IIT Delhi, India.
23. N.R. Jena (2011) How Does AGT Find and Repair its Target on DNA. 20th Conference on current trends in computational chemistry, Jackson, MS, USA.
24. N.R. Jena (2011) GSK-3 as Potential Therapeutic Target, International Conference on “Medichem”, Beijing, China.
25. N.R. Jena (2010) Can Theory Guide Experiment: Substrate Hydroxylation by P450 as an Example. Symposium on “Recent Trends in Biophysics, BHU, Varanasi, India.
26. N.R. Jena (2010) DNA Damage, Its Consequences and Repair. International Conference on “Frontiers in Biological Sciences”, NIT Rourkela, India.
27. N.R. Jena (2010) DNA Repair by Enzymes: Current Progress and Future Challenges. International Conference on “Recent Advances in Bioinformatics”, KIIT, Bhubaneswar, India.
28. N.R. Jena (2009) Substrate Hydroxylation by the P450s: Is There any Consensus Mechanism? 238th ACS Meeting, Washington DC, USA.
29. N.R. Jena (2007) DNA-Protein Interaction: The Good and Bad. Lise-Meitner Minerva Center for Quantum Chemistry, Israel.
30. N.R. Jena (2007) Effects of DNA Modification on Protein Structures. National Conference organized by Lase and Spectroscopy Society of India, Varanasi, India.
31. N.R. Jena (2007) Quantum Computation and Drug Design. National conference organized by Indian Science Congress Association, India.
32. N.R. Jena (2006) Molecular Mechanisms of Cancer: Formation of 8-oxoguanine. National Conference Organized by Indian Science Congress Association, India.
33. N.R. Jena (2005) Peroxynitrite Mediated Formation of Two Highly Mutagenic Agents: A Quantum Computational Study. Humboldt Kolleg, BHU, Varanasi, India.
34. N.R. Jena (2004) A Quantum Mechanical and Density functional Study of Structures and Properties of Some Water Clusters”. National symposium on “Atomic, Molecular structures, interactions and Laser Spectroscopy” BHU, Varanasi, India.

Other Publications:

35. Amino Acids Prevent DNA Damage, Research Highlight, Nature India. (http://www.nature.com/nindia/2009/090428/full/nindia.2009.110.html)

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