Dr. Saltman Adam

Dr. Saltman Adam

MD, PhD

Surgery, Beth Israel Medical Center
Brooklyn, NY, United States of America

plus Speciality

CARDIOTHORACIC SURGERY

Biography:

1. Wit AL, Dillon SM, Coromilas J, Saltman AE, Waldecker B. Anisotropic reentry in the epicardial border zone of myocardial infarcts. Annals of the NY Academy of Sciences 1990;591:86-108.
2. Waldecker B, Coromilas J, Saltman AE, Dillon SM, Wit AL. Overdrive stimulation of functional reentrant circuits causing ventricular tachycardia in the infarcted canine heart: Resetting and entrainment. Circulation 1993;87:1286-1305.
3. Coromilas J, Saltman AE, Waldecker B, Dillon SM, Wit AL. Electrophysiological effects of flecainide on anisotropic conduction and reentry in infarcted canine hearts. Circulation 1995;91:2245-63.
4. Saltman AE, Krukenkamp IB, Gaudette GR, Levitsky S. Pharmacologic preconditioning with pinacidil provides superior electrophysiological and mechanical preservation for the heart undergoing minimally invasive revascularization. Surgical Forum 1996;47:295-297.
5. Saltman AE, Svensson LG. Chronic traumatic aortic pseudoaneurysm: resolution with observation. Annals of Thoracic Surgery 1999;67:240-1. Saltman AE, Dzik WH, Levitsky S. Immediate vein graft thrombectomy for acute occlusion after coronary artery bypass grafting. Annals of Thoracic Surgery 1999;67:1775-6.
6. Horimoto H, Saltman AE, Gaudette GR, Krukenkamp IB. Nitric oxide-generating ?-adrenergic blocker nipradilol preserves postischemic cardiac function. Annals of Thoracic Surgery 1999;68:844-9.
7. Horimoto H, Gaudette GR, Saltman AE, Krukenkamp IB. The role of nitric oxide, KATP channels, and cGMP in the preconditioning response of the rabbit. Journal of Surgical Research 2000;92:56-63.
8. Gaudette GR, Krukenkamp IB, Saltman AE, Horimoto H, Levitsky S. Preconditioning with PKC and the ATP-sensitive potassium channels: a codependent relationship. Annals of Thoracic Surgery, 2000;70:602-8.
9. Saltman AE, Krukenkamp IB, Gaudette GR, Horimoto H, Levitsky S. Pharmacological preconditioning with the adenosine triphosphate-sensitive potassium channel opener pinacidil. Annals of Thoracic Surgery 2000;70:595-601.
10. Saltman AE, Krukenkamp IB, Gaudette GR, Levitsky S. Amrinone preconditioning in the isolated perfused rabbit heart. Annals of Thoracic Surgery 2000;70:609-13. Saltman AE, Chandy J, Gaudette GR, Murtha JJ, Krukenkamp IB. The topical application of anti-inflammatory drugs prevents postoperative atrial fibrillation in a canine model. Surgical Forum 2000;51:76-78.
11. Irie H, Abrahimi A, Abumrad N, Gaudette GR, Saltman AE, Krukenkamp IB. The CD36 protein is an important modulator of ischemia/reperfusion injury in the murine heart. Surgical Forum 2001;52:72-74.
12. Madhavan G, Saltman AE, Thanikachalam S. Ruling the Future: Medico-Surgical Robots. Intech-ISA India Region Journal for Measurement and Control 2002;21:11-15. Madhavan G, Saltman AE: MEMS: A quick look into the breakthrough technology. J Intech, 2002;21:7-9.
13. Char D, Cuadra S, Ricotta J, Bilfinger T, Giron F, McLarty A, Krukenkamp I, Saltman A, Seifert S: Combined coronary artery bypass and carotid endarterectomy: long-term results. Cardiovascular Surgery, 2002;10:111-115.
14. Madhavan G, Thanikachalam S, Krukenkamp I, Saltman A: Robotic Surgeons: Lending a pinpoint precision hand. IEEE Potentials 2002;21: 4-7.
15. Saltman AE, Aksehirli T, Vairgas V, Gaudette G, Matsuyama N, Brink P, Krukenkamp IB. Gap junction uncoupling protects the myocardium from ischemia. Journal of Thoracic and Cardiovascular Surgery 2002;124:371-376.
16. Gaudette GR, Azeloglu EU, Oleszak L, Saltman AE, Krukenkamp IB, Chiang FP. Determination of regional area stroke work with high spatial resolution in the heart. Cardiovascular Engineering: An International Journal 2002;2:129-137.
17. Irie H, Krukenkamp IB, Brinkmann JFF, Gaudette GR, Saltman AE, Jou W, Glatz JFC, Abumrad NA, Ibrahimi A. Myocardial recovery from ischemia is impaired in CD36-null mice and restored by myocyte CD36 expression or medium-chain fatty acids. Proceedings of the National Academy of Sciences 2003;100:6819-6824.
18. Saltman AE. Is it time to choose amiodarone for postoperative atrial fibrillation? Journal of Thoracic and Cardiovascular Surgery 2003;125:1202-1203.
19. Saltman AE, Rosenthal L, Francalancia NA, Lahey SJ. A completely endoscopic approach for ablation of atrial fibrillation. Heart Surgery Forum 2003;6:2003-11333. 20. Irie H, Gao J, Gaudette GR, Cohen IS, Mathias RT, Saltman AE, Krukenkamp IB. Both metabolic inhibition and mitochondrial KATP channel opening are myoprotective and initiate a compensatory sarcolemmal outward membrane current. Circulation 2003;108:II-341-7.
21. Saltman AE, Lahey SJ, Francalancia NA, Tselentakis EV. Origin of atrial fibrillation in a patient who had undergone septal myectomy. Journal of Cardiovascular Electrophysiology 2003;14:786.
22. Ricotta JJ, Char DJ, Cuadra SA, Bilfinger TV, Wall LP, Giron F, Krukenkamp IB, Seifert FC, McLarty AJ, Saltman AE, Komaroff E. Modeling stroke risk after coronary artery bypass and combined coronary artery bypass and carotid endarterectomy. Stroke 2003;34:1212-7.
23. Madhavan G, Gaudette GR, Berube D, Saltman A. Microwaving the heart. IEEE Potentials 2004;23:18-20.
24. Saltman AE. Postoperative atrial fibrillation: A riddle wrapped in a mystery surrounded by an enigma. Journal of Thoracic and Cardiovascular Surgery 2004;127:311-313.
25. Gaudette GR, Krukenkamp IB, Azeloglu EU, Saltman AE, Lense M, Todaro J, Chiang FP. Effects of ischemia on epicardial deformation in the passive rabbit heart. Journal of Biomechanical Engineering 2004;126:70-75.
26. Salenger R, Lahey SJ, Saltman AE. The completely endoscopic treatment of atrial fibrillation: Report on the first 14 cases with early results. Heart Surgery Forum 2004;7:E554-E558.
27. Saltman AE. Completely endoscopic microwave ablation of atrial fibrillation on the beating heart using bilateral thoracoscopy. CTSNet, http://staging.ctsnet.org/sections/clinicalresources/adultcardiac/expert_tech-11.html, 2005. Ciaccio EJ, Saltman AE, Hernandez OM, Bornholdt R, Coromilas J. Multichannel data acquisition system for mapping the electrical activity of the heart. Pacing and Clinical Electrophysiology 2005;28:826-838.
28. Yin W, Krukenkamp IB, Saltman AE, Gaudette G, Suresh K, Bernal O, Jesty J, Bluestein D. The thrombogenic performance of a St. Jude bileaflet MHV in a sheep model ASAIO J. 2006;52:28-33.
29. Azeloglu EU, Yun YH, Saltman AE, Krukenkamp IB, Chiang FP, Chen W, Gaudette GR. High resolution mechanical function in the intact porcine heart: mechanical effects of pacemaker location. Journal of Biomechanics 2006;39:717–725.
30. Tselentakis EV, Woodford E, Chandy J, Gaudette GR, Saltman AE. Inflammation Effects on the Electrical Properties of Atrial Tissue and Inducibility of Postoperative Atrial Fibrillation. Journal of Surgical Research 2006;135:68-75. 31. Badylak SF, Kochupura PV, Cohen IS, Doronin SV, Saltman AE, Gilbert TW, Kelly DJ, Ignotz RA, Gaudette GR. The use of extracellular matrix as an inductive scaffold for the partial replacement of functional myocardium. Cell Transplant. 2006;15 Suppl 1:S29-40.
32. Saltman AE: Surgical options for the treatment of atrial fibrillation: Introduction. Seminars in Thoracic and Cardiovascular Surgery 2007;19:1-2.
33. Saltman AE. Minimally invasive surgery for atrial fibrillation. Seminars in Thoracic and Cardiovascular Surgery 2007;19:33-38.
34. Gillinov AM, Saltman AE. Ablation of atrial fibrillation with concomitant cardiac surgery. Seminars in Thoracic and Cardiovascular Surgery 2007;19:25-32.
35. Gillinov AM, Saltman AE. Surgical approaches for atrial fibrillation. Medical Clinics of North America 2008;92:203-215.
36. Saltman AE, Raju N, Block J. Histopathological evaluation of a novel radiofrequency surgical ablation system. Innovations: Technology & Techniques in Cardiothoracic & Vascular Surgery. 2008;3:47-51.
37. Saltman AE. Completely endoscopic microwave ablation of atrial fibrillation on the beating heart using bilateral thoracoscopy. Surgical Technology International XVII - Cardiovascular Surgery. 2008;17:227-34.
38. Saltman AE, Gillinov AM. Surgical approaches for atrial fibrillation. Cardiol Clin. 2009;27:179-88.
39. Saltman AE. Cardima Surgical Ablation System: a novel tool for cardiac ablation in the treatment of atrial fibrillation. Expert Rev Med Devices. 2009;6:231-236.
Book Chapters, Reviews, Editorials, and Commentaries Saltman AE, Coromilas J, Waldecker B, Dillon SM, Wit AL. Different mechanisms for reentry in the epicardial border zone of healing canine infarcts: The role of functional and anatomic conduction block. In Sideman S, Beyar R, Kléber AG (eds.): Cardiac Electrophysiology, Circulation and Transport. pp. 37-46. Boston: Kluwer Academic, 1991. Saltman AE. Review of: Clinical cardiac pacing and defibrillation (2/e): Ellenbogen K, Kay N, Wilkoff, eds. Cardiovascular Surgery 9:517-518, 2001. Saltman AE. Review of: Beating heart coronary bypass by Salerno T et al. J Intensive Care Medicine 19:60, 2004. Saltman AE, LoCicero J III. Arrhythmias following cardiothoracic operations. In Little AG (ed.): Complications of Cardiothoracic Surgery: Avoidance and Treatment. pp. 48-64. New York, Blackwell Futura, 2004. Saltman AE. Combined off-pump CABG surgery and ablative therapy for atrial fibrillation: Early and mid-term results. Annals of Thoracic Surgery. 2006;81:1337-8,.
40. Saltman AE. Must we cross the wall to get to the other side? J Thorac Cardiovasc Surg. 2006;132:224-5. Saltman AE. Commentary on Williams et al., Laser energy source in surgical atrial fibrillation ablation: preclinical experience. Annals of Thoracic Surgery 2006;82:2260-4.
41. Saltman AE. Surgical therapy for arrhythmias. In Antman EA, Colucci W, Josephson ME (eds): Cardiovascular therapeutics, A companion to Braunwald’s Heart Disease (3/e). pp. 472-480. St. Louis: Elsevier, 2007. Saltman AE. Coupled pacing reverses the effects of persistent atrial fibrillation on the left ventricle. Annals of Thoracic Surgery 2008;86:988. Saltman AE, Gillinov AM. Ablation of atrial fibrillation with cardiac surgery. In Bonser RS, Pagano D, Haverich A, eds. Mitral Valve Surgery. pp.145-154. New York: Springer, 2010. (Bonser RS, Pagano D, Haverich A, eds. Monographs in Cardiac Surgery Series.) Saltman AE. Invited discussion of: Ad et al. Functional protein network mapping of cardiac tissue mitochondria reveals aberrant activation of a common lipogenic glycogenic signaling axis in patients with partial fibrillation. Annual Scientific Meeting of the American Association for Thoracic Surgery, 2012, San Francisco, CA. Abstracts and Presentations Saltman AE, Dillon SM, Ursell PC, Coromilas J, Wit AL. Influence of anisotropic structure of the infarct epicardial border zone on conduction. Fed Proc 1987;46:1438 (FASEB, 1987).
42. Waldecker B, Coromilas J, Saltman AE, et al. Influences of anisotropy on termination of reentrant tachycardia by overdrive pacing in infarcted canine hearts. Circulation 1988;78:II-612 (AHA Scientific Sessions, 1988).
43. Coromilas J, Saltman AE, Waldecker B, Dillon SM, Wit AL. Effect of class IC antiarrhythmic drugs on anisotropic reentry in canine infarcts. Circulation 1988;78:II-460 (AHA Scientific Sessions, 1988).
44. Coromilas J, Saltman AE, Waldecker B, Dillon SM, Wit AL. Transient entrainment of reentrant ventricular tachycardia by overdrive pacing in infarcted canine hearts: Role of site, rate and duration of pacing. Circulation 1989;80:II-146 (AHA Scientific Sessions, 1989).
45. Saltman AE, Coromilas J, Ursell PC, Wit AL. Both functional and anatomic reentry cause ventricular tachycardia in healing myocardial infarcts. Circulation 1990;82:III-453 (AHA Scientific Sessions, 1990).
46. Coromilas J, Saltman AE, Wit AL. Antiarrhythmic drugs on anisotropic reentry in canine infarcts. Circulation 1990;82:III-453 (AHA Scientific Sessions, 1990). 47. Coromilas J, Saltman AE, Wit AL. Antiarrhythmic drugs with class IC action lengthen the central common pathway by converting slow transverse conduction to functional block. Circulation 1992;86:I-133 (AHA Scientific Sessions, 1992)
48. Saltman AE, Horst D, Alseigh N, Bleday R. Retractile mesenteritis and methysergide maleate: A case report and review of the literature (American Society of Colorectal Surgeons, 1995).
49. Kirchhof CJHJ, Saltman AE, Krukenkamp IB, Campos CT, Cohn W, Lahey SJ, Levitsky S, Josephson ME. High-Density Mapping of Chronic Atrial Fibrillation in Man. Circulation 1996;94:I-555 (AHA Scientific Sessions, 1996). Kirchhof CJHJ, Saltman AE, Krukenkamp IB, Campos CT, Cohn W, Lahey SJ, Levitsky S, Josephson ME. Lack of Evidence for Electrophysiological Remodeling in Human Atrial Fibrillation. Circulation 1996;94:I-554 (AHA Scientific Sessions, 1996).
50. Saltman AE, Krukenkamp IB, Gaudette GR, Levitsky S. Amrinone preconditioning provides electrophysiological and mechanical protection from ischemia equivalent to ischemic preconditioning. Circulation 1996;94:I-114 (AHA Scientific Sessions, 1996). 51. Saltman AE, Krukenkamp IB, Gaudette GR, Levitsky S. Phenylephrine reverses the vasodilatory effect of pinacidil preconditioning yet preserves its electrophysiological and mechanical effects. Circulation 1996;94:I-415 (AHA Scientific Sessions, 1996).
52. Saltman AE, Krukenkamp IB, Gaudette GR, Levitsky S. The effect of beta receptor manipulation on ischemic preconditioning. FASEB J 1997;11:A72 (FASEB, 1997).
53. Gaudette GR, Krukenkamp IB, Saltman AE, Horimoto H, Levitsky S. Dobutamine preconditioning reduces infarct size, but has detrimental mechanical and electrophysiological effects. FASEB J 1997;11:A73 (FASEB 1997).
54. Saltman AE, LoCicero J III. Short stay thoracic surgery. Am J Resp Crit Care Med 1997;155:A482 (ALA/ATS, 1997).
55. Saltman AE, Chandy J, Gaudette GR, Murtha JJ, Krukenkamp IB. The topical application of anti-inflammatory drugs prevents postoperative atrial fibrillation in a canine model. Surgical Forum 2000;51:76-78 (ACS Forum on Fundamental Surgical Problems, 2000).
56. Bilfinger TV, Seifert FC, Giron F, McLarty A, Krukenkamp I, Saltman A, Ricotta JJ. Can the added risk of stroke from combined CABG and carotid endarterectomy be predicted? Annals of Thorac Surg, 2001 (Outcomes 2001). Irie H, Ibrahimi A, Abumrad N, Gaudette GR, Saltman AE, Goodman MA, Krukenkamp IB. Fatty acid transport via CD36 is an important mediator of ischemic tolerance in murine heart. Circulation 2001;104:II-474 (AHA Scientific Sessions, 2001).
57. Gaudette GR, Gao J, Cohen IS, Mathias RT, Zuckerman J, Irie H, Saltman AE, Krukenkamp IB. Ischemic preconditioning protects the heart from membrane changes due to ischemia. J Amer Col Cardiol 2002;39:323A (ACC Scientific Sessions, 2002). 58. Tselentakis EV, Gaudette GR, Saltman AE. Inflammation depresses conduction in normal heart tissue. Annals of Biomedical Engineering, 2002. (BMES, 2002).
59. Bluestein D, Yin W, Alemu Y, Jesty J, Saltman AE, Krukenkamp IB, Bernal O, Suresh K. Platelet activation and free emboli formation in flow past mechanical heart valves – numerical and in vivo studies. Annals of Biomedical Engineering, 2002. (BMES, 2002). 60. Gaudette GR, Azeloglu EA, Oleszak L, Ferreri SL, Saltman AE, Krukenkamp IB, Chiang FP. Determination of myocardial function with high spatial resolution in the regionally ischemic beating rabbit heart. Annals of Biomedical Engineering, 2002. (BMES, 2002).
61. Saltman AE, Tselentakis EV, Gaudette GR, Krukenkamp IB. Inflammation and atrial fibrillation: Arachidonic acid depresses conduction in a directionally-dependent manner. Journal of Surgical Research, 2002. (AAS Annual Meeting, 2002).
62. Gaudette GR, Azeloglu E, Saltman AE, Krukenkamp IB, Chiang F-P. Determination of regional function with high spatial resolution in the regionally ischemic heart. Circulation 2002;106:II-158 (AHA Scientific Sessions, 2002).
63. Saltman AE, Tselentakis EV, Gaudette GR, Krukenkamp IB. Inflammation and atrial fibrillation: Arachidonic acid depresses conduction velocity in a fiber direction dependent manner. Circulation 2002;106:II-344 (AHA Scientific Sessions, 2002).
64. Saltman AE, Seifert FC, Bilfinger TV, McLarty AJ, Krukenkamp IB. Microwave ablation of atrial fibrillation: Early clinical experience. Circulation 2002;106:II-669 (AHA Scientific Sessions, 2002).
65. Saltman AE. A completely endoscopic approach to the ablation of atrial fibrillation. (New Era Conference, 2003). Saltman AE, Simsir S, Lahey SJ, Francalancia NA. A completely endoscopic approach to the ablation of atrial fibrillation. (Cardiothoracic Techniques and Technologies, Miami, 2003).
66. Azeloglu EU, Yun YH, Gaudette GR, Saltman AE, Krukenkamp IB, Chiang FP. Regional mechanical effects of pacing in the intact porcine heart. (Northeast Bioengineering Conference, 2003).
67. Karnik A, Saltman AE, Ye K, Tselentakis EV, Gaudette GR, Dhundale A. A DNA microarray survey for gene expression changes in atrial fibrillation. JACC 2003;41:274A,. (American College of Cardiology Annual Scientific Sessions, 2003). Saltman AE. Automated laser ablation for closed-chest lone atrial fibrillation treatment. (New Era Cardiac Care, 2007).
68. Saltman AE, Guyette JP, Kelly D, Filipe DV, Murphy MK, Singh D, McBride NS, Pins GD, Oray BN, Gaudette GR. A regenerative cardiac scaffold for use in ventricular remodeling. Heart Surgery Forum 2008;11(I):S161 (World Congress of Cardiothoracic Surgery, 2008). S
69. altman AE, Patel M, Agarwal A, Cantu A. Multi-device comparison trial of five different energy sources in a clinically relevant model: Study on lesion width, depth, volume and the effect of epicardial fat. Heart Surgery Forum 2008;11(I):S114 (World Congress of Cardiothoracic Surgery, 2008)
70.Saltman AE, Virmani R, Mohan AA. Development and testing of a novel device for left atrial appendage occlusion. Heart Surgery Forum 2008;11(I):S82 (World Congress of Cardiothoracic Surgery, 2008)
71. Saltman AE, Guyette JP, Kelly D, Filipe DV, Murphy MK, Singh D, McBride NS, Pins GD, Oray BN, Gaudette GR. A pericardial-based bioscaffold promotes ventricular remodeling and regeneration. Innovations, 2008. (International Society for Minimally Invasive Cardiothoracic Surgery, 2008).
72. Saltman AE, Patel M, Agarwal A, Cantu A, Johnson K, Brucker G. Multi-device comparison trial of five different energy sources in a clinically relevant model. Innovations, 2008. (International Society for Minimally Invasive Cardiothoracic Surgery, 2008)
73. Saltman AE, Virmani R, Mohan AA. Development and testing of a novel device for left atrial appendage occlusion. Innovations, 2008. (International Society for Minimally Invasive Cardiothoracic Surgery, 2008)

Academic positions:

1. Jan 1999-Aug 2002: Assistant Professor of Surgery Stony Brook University
2. Jan 1999-Aug 2002: Assistant Professor of Physiology & Biophysics Stony Brook University
3. Jan 1999-Aug 2002: Director of Surgical Electrophysiology Stony Brook University  4. Jan 1999-Aug 2002: Member, Institute for Molecular Cardiology Stony Brook University
5. Jan 1999-Aug 2002: Director of CT Surgery Education Stony Brook University  
6. July 2000-Aug 2002: Adj. Asst. Prof. of Biomedical Engineering Stony Brook University
7. Aug 2002-May 2006: Associate Professor of Surgery Univ. of Massachusetts
8. Aug 2002-May 2006: Associate Professor of Physiology Univ. of Massachusetts  
9. July 2003-May 2006: Affil.Assoc. Prof. of Biomedical Engineering Worcester Polytech Inst.
10. Aug 2002-May 2006: Director of CT Surgery Research & Education UMass Memorial  
11. July 2003-May 2006: Member, Bioengineering Institute Worcester Polytech Inst  
12. Nov 2002, April 2003: Honorary Consultant Cardiothoracic Surgeon James Cook Hospital
13. Mar 2005-May 2006: CT Surgery Residency Program Director Univ. of Massachusetts  
14. April 2006-present Research Assoc. Prof. of Biomedical Engineering Worcester Polytech Inst.
15. May 2006-May 2009: Director, Atrial Fibrillation Center Maimonides Med Ctr.  
16. May 2006-May 2009: Director, CT Surgery Research Maimonides Med Ctr.  
17. May 2006-May 2009: Director, Surgical Electrophysiology Maimonides Med Ctr.
18. Aug 2008-present: Associate Professor of Surgery SUNY/Downstate 

Research interests:

Surgical therapy of cardiac arrhythmias Effect of inflammation on electrical conduction in the heart Mechanisms, prevention and treatment of postoperative atrial fibrillation Genetic alterations in atrial fibrillation Pharmacologic mechanisms of myocardial preconditioning Electrophysiology of ischemic and pharmacological preconditioning Development and implementation of myocardial replacement materials New devices for left atrial appendage closure Anti-oxidant effects on myocardial ischemia Anti-oxidant effects on wound healing

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Very interesting way of quickly disseminating important information; however, I think that the Plus idea of post-publication review is fascinating and may be a good model for the future of medical publication and communication.