Prof. Weiler Catherine

Prof. Weiler Catherine

Assistant Professor of Medicine

Immunology at Mayo Clinic
Rochester, Minnesota Area , United States of America

plus Speciality




1. 1984 – 1989: Doctor of Philosophy (Ph.D.), Immunology, Mayo Clinic

2. 1976 – 1983: Doctor of Medicine (MD), Medicine and surgery; Kuwait university Faculty of Medicine

Academic positions:

Experience: 1. July 1998 – Present (14 years 4 months): Consultant; Mayo Clinic Allergy and immunology. Sub specialty hyper eosinophilic syndrome, eosinophilic esophagitis, eosinophilic gastrointestinal disorders, systemic mastocytosis, mast cell activation disorders and anaphylaxis. 2. April 1998 – Present (14 years 7 months): Assistant Professor of Medicine; Mayo Clinic 3. March 1984 – May 1998 (14 years 3 months): Graduate School and medical training; Mayo Clinic Graduate school: immunology of eosinophil degranulation and activation Postdoctoral training: biochemistry and biophysics of eosinophil proteins Residency: internal medicine Fellowship: allergy and immunology 4. June 1997 – July 1997 (2 months): Fellowship sub training; Duke University Primary immunodeficiency

Research interests:

Immunology, Asthma, Internal Medicine, Pediatrics, EMR, Medical Education, Clinical Research, Healthcare.

Any other information:

Peer-reviewed Articles

1. Fujisawa T, Uchida Y, Abu-Ghazaleh RI, Gleich GJ.  The effect of cytokines on eosinophil degranulation.  38th Annual Meeting Japanese Society of Allergology Kyoto Japan. 1988.
2. Abu-Ghazaleh RI, Fujisawa T, Mestecky J, Kyle RA, Gleich GJ.  IgA-induced eosinophil degranulation.  J Immunol. 1989 Apr 1; 142(7):2393-400.  PMID:2926137.
3. Fujisawa T, Abu-Ghazaleh R, Kita H, Sanderson CJ, Gleich GJ.  Regulatory effect of cytokines on eosinophil degranulation.  J Immunol. 1990 Jan 15; 144(2):642-6.  PMID:2104901.
4. Kita H, Abu-Ghazaleh R, Sanderson CJ, Gleich GJ.  Effect of steroids on immunoglobulin-induced eosinophil degranulation.  Journal of Allergy & Clinical Immunology. 1991 Jan; 87(1 Pt 1):70-7.  PMID:1991924.
5. Kita H, Abu-Ghazaleh RI, Gleich GJ, Abraham RT.  Regulation of Ig-induced eosinophil degranulation by adenosine 3',5'-cyclic monophosphate.  J Immunol. 1991 Apr 15; 146(8):2712-8. PMID:1707917.
6. Kita H, Abu-Ghazaleh RI, Gleich GJ, Abraham RT.  Role of pertussis toxin-sensitive G proteins in stimulus-dependent human eosinophil degranulation.  J Immunol. 1991 Nov 15; 147(10):3466-73.  PMID:1719078.
7. Abu-Ghazaleh RI, Kita H, Gleich GJ.  Eosinophil activation and function in health and disease.  Immunol Ser. 1992; 57:137-67.  PMID:1504137.
8. Abu-Ghazaleh RI, Gleich GJ, Prendergast FG.  Interaction of eosinophil granule major basic protein with synthetic lipid bilayers: a mechanism for toxicity.  J Membr Biol. 1992 Jun; 128(2):153-64.  PMID:1501242.
9. Kita H, Weiler DA, Abu-Ghazaleh R, Sanderson CJ, Gleich GJ.  Release of granule proteins from eosinophils cultured with IL-5.  J Immunol. 1992 Jul 15; 149(2):629-35.  PMID:1624806.
10. Abu-Ghazaleh RI, Dunnette SL, Loegering DA, Checkel JL, Kita H, Thomas LL, Gleich GJ.  Eosinophil granule proteins in peripheral blood granulocytes.  J Leukoc Biol. 1992 Dec; 52(6):611-8.  PMID:1464733.
11. Kita H, Abughazaleh RI, Sur S, Gleich GJ.  Eosinophil major basic protein induced degranulation and IL-8 production by human eosinophils.  J Immunol. 1995 May 1; 154:4749-4758. PMID:7722326.
12. Weiler CR, Kita H, Hukee M, Gleich GJ.  Eosinophil viability during immunoglobulin-induced degranulation.  J Leukoc Biol. 1996 Oct; 60(4):493-501.  PMID:8864134.
13. Kubo H, Loegering DA, Tohda Y, Bankers-Fulbright J, Weiler CR, Nakajima H, Thomas LL, Adolphson CR, Gleich GJ.  Discordant and anomalous results among cytotoxicity assays: the confounding properties of eosinophil granule major basic protein on cell viability assays.  J Immunol Methods. 1999 Jul 30; 227(1-2):1-15.  PMID:10485250.
14. Papouchado BG, Chapoval SP, Marietta EV, Weiler CR, David CS.  HLA-DQ/human CD4-restricted immune response to cockroach allergens in transgenic mice.  Tissue Antigens. 2000 Apr; 55(4):303-11.  PMID:10852381.
15. Steensma DP, Tefferi A, Weiler CR.  Autoimmune hemolytic anemia in a patient with autosomal dominant chronic mucocutaneous candidiasis.  Mayo Clin Proc. 2000 Aug; 75(8):853-5.  PMID:10943243.
16. Thomas LL, Kubo H, Loegering DJ, Spillard K, Weaver AJ, McCormick DJ, Weiler C, Gleich GJ.  Peptide-based analysis of amino acid sequences important to the biological activity of eosinophil granule major basic protein.  Immunol Lett. 2001 Oct 1; 78(3):175-81.  PMID:11578692.
17. Papouchado BG, Chapoval SP, Marietta EV, Weiler CR, David CS.  Cockroach allergen-induced eosinophilic airway inflammation in HLA-DQ/human CD4(+) transgenic mice.  J Immunol. 2001 Oct 15; 167(8):4627-34.  PMID:11591792.
18. Phy JL, Weiss WT, Weiler CR, Damario MA.  Hypersensitivity to progesterone-in-oil after in vitro fertilization and embryo transfer.  Fertil Steril. 2003 Nov; 80(5):1272-5.  PMID:14607588.
19. Weiler CR.  Immunoglobulin therapy: history, indications, and routes of administration.  Int J Dermatol. 2004 Mar; 43(3):163-6.  PMID:15009382.
20. Eberhart AH, Weiler CR, Erie JC.  Angioedema related to the use of hyaluronidase in cataract surgery.  Am J Ophthalmol. 2004 Jul; 138(1):142-3.  PMID:15234297. DOI:10.1016/j.ajo.2004.02.035.
21. Babovic-Vuksanovic D, Jacobson RM, Lindor NM, Weiler CR.  Selective antibody immune deficiency in a patient with Smith-Lemli-Opitz syndrome.  J Inherit Metab Dis. 2005; 28(2):181-6.  PMID:15877207.
22. Weiler CR, Bankers-Fulbright JL.  Common variable immunodeficiency: test indications and interpretations.  Mayo Clin Proc. 2005 Sep; 80(9):1187-200.  PMID:16178499.
23. Orange JS, Hossny EM, Weiler CR, Ballow M, Berger M, Bonilla FA, Buckley R, Chinen J, El-Gamal Y, Mazer BD, Nelson RP Jr, Patel DD, Secord E, Sorensen RU, Wasserman RL, Cunningham-Rundles C, Primary Immunodeficiency Committee of the American Academy of Allergy Asthma and Immunology. Use of intravenous immunoglobulin in human disease: a review of evidence by members of the Primary Immunodeficiency Committee of the American Academy of Allergy, Asthma and Immunology.  J Allergy Clin Immunol. 2006 Apr; 117(4 Suppl):S525-53.  PMID:16580469. DOI:10.1016/j.jaci.2006.01.015.
24. Weiler CR, van Dellen RG.  Genetic test indications and interpretations in patients with hereditary angioedema.  Mayo Clin Proc. 2006 Jul; 81(7):958-72.  PMID:16835976.
25. Cheng YK, Decker PA, O'Byrne MM, Weiler CR.  Clinical and laboratory characteristics of 75 patients with specific polysaccharide antibody deficiency syndrome.  Ann Allergy Asthma Immunol. 2006 Sep; 97(3):306-11.  PMID:17042135.
26. Karakelides M, Monson KL, Volcheck GW, Weiler CR.  Monoclonal gammopathies and malignancies in patients with chronic urticaria.  Int J Dermatol. 2006 Sep; 45(9):1032-8.  PMID:16961504. DOI:10.1111/j.1365-4632.2006.02982.x.
27. Swoger JM, Weiler CR, Arora AS.  Eosinophilic esophagitis: is it all allergies?  Mayo Clin Proc. 2007 Dec; 82(12):1541-49.  PMID:18053464.
28. Butterfield JH, Weiler CR.  Prevention of mast cell activation disorder-associated clinical sequelae of excessive prostaglandin D(2) production.  Int Arch Allergy Immunol. 2008; 147(4):338-43. Epub 2008 Jul 12.  PMID:18622141. DOI:10.1159/000144042.
29. Lee J, Dierkhising R, Wu TT, Alexander J, Weiler C.  Eosinophilic gastrointestinal disorders (EGID) with peripheral eosinophilia: a retrospective review at Mayo Clinic.  Dig Dis Sci. 2011 Nov; 56(11):3254-61. Epub 2011 Jun 08.  PMID:21655949. DOI:10.1007/s10620-011-1754-3.
30. Sridhara S, Ravi K, Smyrk TC, Kita H, Kephart GM, Weiler C, Katzka DA.  Increased Numbers of Eosinophils, Rather than Only Etiology, Predict Histologic Changes in Patients with Esophageal Eosinophilia.  Clin Gastroenterol Hepatol. 2012 Jan 27. [Epub ahead of print]  PMID:22289868. DOI:10.1016/j.cgh.2012.01.008.
31. Butterfield JH, Weiler CR.  Use of pegylated interferon in hypereosinophilic syndrome. Leuk Res. 2012 Feb; 36(2):192-7. Epub 2011 Nov 26.  PMID:22118911. DOI:10.1016/j.leukres.2011.09.026.

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