Dr. Singh Pankaj

Dr. Singh Pankaj

Postdoctoral Fellow

Experimental Radiation Oncology, MD Anderson Cancer Center
Houston, Texas, United States of America

plus Speciality

APOPTOSIS

Biography:

I am a Radiation Oncology Researcher and currently employed at the University of Texas MD Anderson Cancer Center, Houston as a senior post-doctoral research associate. I have more than 12 years of extensive experiences in the field of radiation biology, radiation countermeasures development, and radiation oncology. I have published more than 25 peer reviewed publications in reputed journals with 178 citations, 8 h-index, and 8 i10-index. I am the recipient of numerous awards/recognitions for my research work. My CV is attached herewith for your kind reference.

I am in the editorial team of Journal of Molecular Biology (OMICS group). I have reviewed several manuscripts for the journals publishing in the field of life-sciences, radiation biology, radiation oncology, and cancer including Journal of Radiation Research, Radiation Research, International Journal of Radiation Biology, British Journal of Cancer, Radiotherapy and Oncology, Integrative Cancer Therapy, BioMed Research International, PlosOne, and many more.

Academic positions:

Academic Qualifications

1. 2008: Doctoral; Biotechnology; Institute of Nuclear Medicine & Allied Sciences (INMAS) and Hamdard University, Delhi
2. 2002: Master; Biotechnology; Indian Institute of Technology (IIT), Roorkee
3. 2000: Bachelor; Biotechnology; Patna University, Patna

Professional Experience

1. Nov 2012-till date: Postdoctoral Fellow; Experimental Radiation Oncology, MD Anderson
Cancer Center, Houston, Texas, USA
2. Nov 2009-Nov 2012: Resident Research Associate; Armed Forces Radiobiology Research Institute, Uniformed Services University of the Health Sciences,  Bethesda, MD, USA
3. May 2009-November 2009: Senior Specialist; National Disaster Management Authority (NDMA), Delhi, India
4. Jan 2005 - Dec. 2007: Senior Research Fellow; Institute of Nuclear Medicine and Allied
Sciences (INMAS), Delhi, India
5. Jan 2003 - Dec 2004: Junior Research Fellow; Institute of Nuclear Medicine and Allied
Sciences (INMAS), Delhi, India

Awards and Fellowships

Academic Awards/Fellowships:

• Post-Doctoral Fellowship from the University of Texas, MD Anderson Cancer Center, Houston, Texas, USA (2012).
• Post-Doctoral Fellowship from National Research Council, National Academy of Sciences, USA (2009).
• Junior Research Fellowship award from Indian Council of Medical Research (ICMR), (Jan 2003 - Dec 2004)
• Senior Research Fellowship award from Indian Council of Medical Research (ICMR), (Jan 2004- Dec 2007)
• Qualified National Eligibility Test (2002), conducted by Council of Scientific and Industrial Research (CSIR).
• Qualified Graduate Aptitude Test in Engineering (GATE-2002) with 89.5% Score.
• Fellowship from Department of Biotechnology (DBT), India, for pursuing M.Sc Biotechnology degree from IIT Roorkee (Aug. 2000 to May 2002).

Awards at Symposia/Conferences:

• Scholars-in-Training (SIT) Travel Award from the Radiation Research Society, Lawrence, KS, USA (2012).
• Best poster paper award (2007) received at 48th annual conference of Association of microbiologist of India held at Chennai.
• Best oral presentation award received from INMAS (2005) held at Delhi.

Certifications/Memberships:

• Member of the Radiation Research Society (RRS), USA. (2011-till date).
• Life member of  Indian society for Radiation Biology, Delhi India
• Certification course for working safely with Nonhuman Primates from American Association for Laboratory Animal Science (AALAS) at Armed Forces Radiobiology Research Institute, 2012.
• Certification course for ALAT 2: The Research Facility Environment from American Association for Laboratory Animal Science (AALAS) at Armed Forces Radiobiology Research Institute, 2012
• Certification course for The Animal Research Environment from American Association for Laboratory Animal Science (AALAS) at Armed Forces Radiobiology Research Institute, 2012
• Attended Continuing Education Program (CEP) course on Herbs for Health: Application in Armed Forces, 2006.
• Attended Continuing Education Program (CEP) course on Herbal Drug Research, 2005.

Research interests:

Radiation Biology, Radiation protection, Radiation Countermeasure, Radiation oncology, Radiation and DNA damage response, Radiosensitization, Apoptosis, Cell cycle regulation, Identification of novel molecular targets and pathways for therapeutics

Any other information:

Publications

Research Papers

1. Kulkarni S, Singh PK, Ghosh SP, Posarac A, Singh VK. Granulocyte colony-stimulating factor antibody abrogates radioprotective efficacy of gamma-tocotrienol, a promising radiation countermeasure. Cytokine. 2013 May;62(2):278-85.
2. Singh VK, Wise SY, Singh PK, Posarac A, Fatanmi OO, Ducey EJ, Bolduc DL, Elliott TB, Seed TM. Alpha-tocopherol succinate-mobilized progenitors improve intestinal integrity after whole body irradiation. Int J Radiat Biol. 2013 May;89(5):334-45.
3. Singh VK, Singh PK, Wise SY, Posarac A, Fatanmi OO. Radioprotective properties of tocopherol succinate against ionizing radiation in mice. J Radiat Res. 2013 Mar 1;54(2):210-20.
4. Singh VK, Wise SY, Singh PK, Ducey EJ, Fatanmi OO, Seed TM. α-Tocopherol succinate- and AMD3100-mobilized progenitors mitigate radiation-induced gastrointestinal injury in mice. Exp Hematol. 2012 May;40(5):407-17. IF 3.2
5. Singh VK, Fatanmi OO, Singh PK, Whitnall MH. Role of radiation-induced granulocyte colony-stimulating factor in recovery from whole body gamma-irradiation. Cytokine. 2012 Jun;58(3):406-14. IF 3.5
6. Singh VK, Ducey EJ, Fatanmi OO, Singh PK, Brown DS, Purmal A, Shakhova VV, Gudkov AV, Feinstein E, Shakhov A. CBLB613: A TLR 2/6 Agonist, Natural Lipopeptide of Mycoplasma arginini , as a Novel Radiation Countermeasure. Radiat Res. 2012 May;177(5):628-42. IF 2.9
7. Singh PK, Wise SY, Ducey EJ, Fatanmi OO, Elliott TB, Singh VK. α-Tocopherol succinate protects mice against radiation-induced gastrointestinal injury. Radiat Res. 2012 Feb;177(2):133-45. IF 2.9
8. Singh PK, Kumar R, Sharma A, Arora R, Chawla R, Jain SK, Tripathi RP, Sharma RK. Role of Apoptotic Proteins in REC-2006 Mediated Radiation Protection in Hepatoma Cell Lines. Evid Based Complement Alternat Med. 2011;2011:758326. IF 2.1
9. Singh PK, Wise SY, Ducey EJ, Brown DS, Singh VK. Radioprotective efficacy of tocopherol succinate is mediated through granulocyte-colony stimulating factor. Cytokine. 2011 Nov;56(2):411-21. IF 3.5
10. Singh PK, Kumar R, Sharma A, Arora R, Chawla R, Jain SK, Sharma RK. Podophyllum hexandrum fraction (REC-2006) shows higher radioprotective efficacy in the p53-carrying hepatoma cell line: a role of cell cycle regulatory proteins. Integr Cancer Ther. 2009 Sep;8(3):261-72. IF 1.7
11. Singh PK, Kumar R, Sharma A, Arora R, Jain SK, Sharma RK. Pifithrin-alpha decreases the radioprotective efficacy of a Podophyllum hexandrum Himalayan mayapple fraction REC-2006 in HepG2 cells. Biotechnol Appl Biochem. 2009 Jul 9;54(1):53-64. IF 1.9
12. Gupta ML, Sankhwar S, Verma S, Devi M, Samanta N, Agrawala PK, Kumar R, Singh PK. Whole body protection to lethally irradiated mice by oral administration of semipurified fraction of Podophyllum hexandrum and post irradiation treatment of Picrorhiza kurroa. Tokai Journal of Experimental and Clinical Medicine 2008; 33: 6-12.
13. Sagar RK, Chawla R, Arora R, Singh S, Krishna B, Sharma RK, Puri SC, Singh PK. Protection of the hemopoietic system by Podophyllum hexandrum against gamma radiation-induced damage. Planta Medica-Natural Products and Medicinal Plant Research 2006; 72 (2): 114-120. IF 2.4
14. Kumar R, Singh PK, Arora R, Sharma A, Prasad J, Sagar R, Singh S, Sharma RK. Radioprotection by Podophyllum hexandrum in the liver of mice: A mechanistic approach. Environ Toxicol Pharmacol. 2005; 20(2): 326-34. IF 1.4
15. Kumar R, Singh PK, Sharma A, Prasad J, Sagar R, Singh S, Arora R, Sharma RK. Podophyllum hexandrum (Himalayan mayapple) extract provides radioprotection by modulating the expression of proteins associated with apoptosis. Biotechnol Appl  Biochem. 2005; 42(Pt 1): 81-92. IF 1.9

Review Papers

1. Chatterjee DK, Wolfe T, Lee J, Brown AP, Singh PK, Bhattarai SR, Diagaradjane P, Krishnan S, Convergence of nanotechnology with radiation therapy—insights and implications for clinical translation. Transl Cancer Res. 2013; 2(4):256-268.
2. Singh VK, Singh PK, Wise SY, Seed TM. Mobilized progenitor cells as a bridging therapy for radiation casualties: a brief review of Tocopherol succinate-based approaches. Int Immunopharmacol. 2011; 11(7): 842-47. IF 2.3
3. Singh VK, Brown DS, Singh PK, Seed TM. Progenitor cells as a Bridging Therapy for Radiation Casualties. Defence Science Journal 2011; 61 (2): 118-124. IF 0.3
4. Chawla R, Sharma RK, Madaan D, Dubey N, Arora R, Goel R, Singh S, Kaushik V, Singh PK, Chabbra V, Bhardwaj JR. Mitigation approaches to combat the flu pandemic. J Glob Infect Dis. 2009; 1(2): 117-30.
5. Kumar R, Singh PK, Arora R, Chawla R, Sharma RK. Radioprotective activities of Podophyllum hexandrum: current knowledge of the molecular mechanisms. Trees 2008: 4: 1.

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